(2R)-6-ammonio-2-[(tert-butoxycarbonyl)amino]hexanoate
Boc-D-Lys-OH
CAS: 106719-44-2
Molecular Formula: C11H22N2O4
(2R)-6-ammonio-2-[(tert-butoxycarbonyl)amino]hexanoate - Names and Identifiers
| Name | Boc-D-Lys-OH |
| Synonyms | Boc-D-Lys-OH BOC-D-LYSINE BOC-D-LYS-OH N2-Boc-D-lysine N-α-Boc-D-lysine N-.ALPHA.-BOC-D-LYSINE N-tert-Butoxycarbonyl-D-lysine N-ALPHA-T-BUTOXYCARBONYL-D-LYSINE N-ALPHA-T-BUTYLOXYCARBONYL-D-LYSINE NALPHA-tert-Butoxycarbonyl-D-lysine N~2~-(tert-butoxycarbonyl)-L-lysine N-ALPHA-TERT-BUTYLOXYCARBONYL-D-LYSINE (2R)-6-ammonio-2-[(tert-butoxycarbonyl)amino]hexanoate |
| CAS | 106719-44-2 |
| EINECS | 237-303-4 |
| InChI | InChI=1/C11H22N2O4/c1-11(2,3)17-10(16)13-8(9(14)15)6-4-5-7-12/h8H,4-7,12H2,1-3H3,(H,13,16)(H,14,15)/t8-/m1/s1 |
(2R)-6-ammonio-2-[(tert-butoxycarbonyl)amino]hexanoate - Physico-chemical Properties
| Molecular Formula | C11H22N2O4 |
| Molar Mass | 246.3 |
| Density | 1.113±0.06 g/cm3(Predicted) |
| Melting Point | 198 °C |
| Boling Point | 410.5±40.0 °C(Predicted) |
| Flash Point | 202°C |
| Vapor Presure | 6.91E-08mmHg at 25°C |
| Appearance | White to yellow to brown powder or crystal |
| pKa | 3.92±0.21(Predicted) |
| Storage Condition | 2-8°C |
| Refractive Index | -22 ° (C=2, MeOH) |
| MDL | MFCD00076956 |
(2R)-6-ammonio-2-[(tert-butoxycarbonyl)amino]hexanoate - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S4 - Keep away from living quarters. S7 - Keep container tightly closed. S28 - After contact with skin, wash immediately with plenty of soap-suds. S35 - This material and its container must be disposed of in a safe way. S44 - |
| WGK Germany | 3 |
| HS Code | 29241990 |
(2R)-6-ammonio-2-[(tert-butoxycarbonyl)amino]hexanoate - Introduction
N-(tert-butoxycarbonyl)-D-lysine, also known as TBOC-D-lysine, is an amino acid derivative. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline powder.
-Solubility: Soluble in organic solvents such as chloroform, dimethyl sulfoxide and methanol, slightly soluble in water.
-Property stability: It has good thermal stability and light stability.
Use:
-Chemical synthesis: TBOC-D-lysine can be used as a protecting group to prevent non-specific reactions in peptide synthesis.
-Drug research: TBOC-D-lysine can be used to synthesize and study peptide drugs or bioactive peptide derivatives.
-Biochemistry: TBOC-D-lysine can be used in biochemical research to study the interaction between proteins and amino acids.
Preparation Method:
TBOC-D-lysine is generally prepared by the following steps:
1. N-protection: D-lysine is reacted with tert-butylfluoroformate or tert-butylchloroformate to protect the amino group as a tert-butoxycarbonyl group.
2. Ion Exchange: The obtained N-protected product is subjected to ion exchange with an alkali metal salt or hydrochloric acid.
3. Crystallization: The desired product is obtained by solvent crystallization, etc.
Safety Information:
TBOC-D-Lysine is a chemical that requires the following safety precautions:
-Contact: Avoid direct contact with skin, eyes and respiratory tract. If contact occurs, rinse immediately with plenty of water and seek medical assistance.
-Storage: It should be stored in a sealed container, away from direct sunlight and humid environment. Keep a well-ventilated place.
-Waste Disposal: Disposal in accordance with local regulations and do not dump or throw into the trash.
Please note that the above information is for reference only. Please consult the relevant literature and chemical safety data sheets before use, and operate under the guidance of a laboratory or professional.
Nature:
-Appearance: White crystalline powder.
-Solubility: Soluble in organic solvents such as chloroform, dimethyl sulfoxide and methanol, slightly soluble in water.
-Property stability: It has good thermal stability and light stability.
Use:
-Chemical synthesis: TBOC-D-lysine can be used as a protecting group to prevent non-specific reactions in peptide synthesis.
-Drug research: TBOC-D-lysine can be used to synthesize and study peptide drugs or bioactive peptide derivatives.
-Biochemistry: TBOC-D-lysine can be used in biochemical research to study the interaction between proteins and amino acids.
Preparation Method:
TBOC-D-lysine is generally prepared by the following steps:
1. N-protection: D-lysine is reacted with tert-butylfluoroformate or tert-butylchloroformate to protect the amino group as a tert-butoxycarbonyl group.
2. Ion Exchange: The obtained N-protected product is subjected to ion exchange with an alkali metal salt or hydrochloric acid.
3. Crystallization: The desired product is obtained by solvent crystallization, etc.
Safety Information:
TBOC-D-Lysine is a chemical that requires the following safety precautions:
-Contact: Avoid direct contact with skin, eyes and respiratory tract. If contact occurs, rinse immediately with plenty of water and seek medical assistance.
-Storage: It should be stored in a sealed container, away from direct sunlight and humid environment. Keep a well-ventilated place.
-Waste Disposal: Disposal in accordance with local regulations and do not dump or throw into the trash.
Please note that the above information is for reference only. Please consult the relevant literature and chemical safety data sheets before use, and operate under the guidance of a laboratory or professional.
Last Update：2024-04-09 19:05:44
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CAS: 106719-44-2
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CAS: 106719-44-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
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